I had a c3500 4 for dually with the 454. It hauled my heavy 11.5' cab over camper easily. I was probably around 10k lb and could do 75 up huge grades. I sold that and got a 24' motorhome, e450 with the 7.3 psd, 13500lb. It's loud, and "slow". There is no intercooler on the van version, and that costs a lot of power. I drive off the egt gauge. I tune Ford's and could slap a tune on it for free, but it's already at the limit. 4" straight exhaust too. I get 10mpg over a dozen full ups. I talked to a guy with the v10 and nearly identical rv, said he gets 6!
I wanted a boat, so I needed a truck to pull it. I drove the ram trucks, gas then diesel, back to back, both brand new. I liked the hemi better. The diesel seems slow, and the hemi sounds way cooler. Then I drove a used ram with the Cummins. Loud AF, shaking at idle.
Down in socal there is not a lot of diesel. Usually if a station even has it, it's only at one pump.
Down here is not like Texas, diesel trucks are rare, and demand a huge premium. Looking at used trucks under 20k, the diesel seemed to be about $10k+ or 100k miles more compared to the gas.
I ended up with an excursion with the v10. Tons of power, tows easily up any grade, quite except at wot, and any pump works. It gets about 10mpg loaded or not.