@TOGA had the same exact thing happen on a 2013 ecoboost at 80k miles, luckily not while towing. Saw the rod sticking out the side of the block and knew it was bad. Since truck was out of warranty, dealer was only interested in taking it as a trade on a new truck. Not sure why anyone would buy the same truck when their well-maintained engine just blew up for no good reason.
Found an independent shop through friends, owner sent a picture of 4 ecoboosts with the same issue that he was dropping crate engines in... THAT WEEK!! Said he does 10 crate engines in F150s a month...
Long story short, the turbos on these do not have post-oilers, the bearings get loose, impeller blows up, gets ingested into the engine which throws a rod about 60% of the time.
I loved the ecoboost until it self-destructed. It’s still in the family since it has a brand new engine and is completely worthless, but when I got my new truck this year, I went with GMC and a boring old v8 ?